8:50 - 9:25
Speeches by governmental officer and organizer 市领导与主持人致辞
9:25 - 9:30
Open ceremony of CADD center in ZIAT 珠海院人工智能药物研发中心成立揭牌仪式
9:30 - 10:10
Living in the cell: Understand SARS-CoV-2 replication and transcription from structures
Zihe Rao (Tsinghua University, Institute of Biophysics CAS, ShanghaiTech University) 饶子和 （清华大学、中科院生物物理所、上海科技大学）
10:10 - 10:40
From computational pharmacy to modern drug discovery
Shuguang Yuan (Shenzhen Institutes of Advanced Technology, CAS) 袁曙光 （中科院深圳先进技术研究院）
10:40 - 11:00
(Tea break & Poster) 茶歇与海报交流
11:00 - 11:30
Protein flexibility and drug design
(Tingjun Hou, Zhejiang University) 侯廷军 （浙江大学）
11:30 - 12:00
Molecular mechanism for ligand recognition and subtype selectivity of alpha2 adrenergic receptors
(Dong Wu, Zhuhai Institutes of Advanced Technology) 武栋 （珠海先进技术研究院）
12:00 - 12:30
Multi-national Corporation’s Business Development Innovation Model
Mos Mo (Merck Innovation Center) 莫凌霄 (德国默克创新中心)
12:30 - 14:00
(lunch and break) 午餐与休闲
14:00 - 14:30
Transmembrane signaling by ligand-gated ion channels
Horst Vogel (Shenzhen Institutes of Advance Technology, CAS, 中科院深圳先进技术研究院、EPFL)
14:30 - 15:00
Medicinal chemistry and drug discovery targeting aminergic GPCRs
Jianjun Chen (ShanghaiTech University) 程建军 （上海科技大学）
15:00 - 15:30
Boosting pharmaceutical industry in Basel Area
BaselArea Business & Innovation巴塞尔大区经济和创新促进局
15:30 - 15:50
(Tea break & Poster) 茶歇与海报交流
15:50 - 16:10
Partition of Drug-like Molecules in Cell Membrane
Hao Dong (Nanjing University) 董昊 （南京大学）
16:10 - 16:30
Thermodynamic and kinetic studies on the coupled folding and binding mechanisms of intrinsically disordered protein
Rongfeng Zou (Shenzhen Institutes of Advance Technology, CAS) 邹荣峰 （中科院深圳先进技术研究院）
16:30 - 17:00
On the Valence Selectivity of Ryanodine Receptors: A Molecular Dynamics Simulation Study
Chen Song (Peking University) 宋晨 （北京大学）
17:00 - 18:00
Bridging Academic research and industry with novel biotechnology
industrial-academic round table forum企业-学术圆桌论坛
9:00 - 9:40
Glucagon-like peptide-1 receptor: small molecule agonists, 3-dimentional structures and beyond
Mingwei Wang (Fudan University) 王明伟 （复旦大学）
9:40 - 10:10
Discovery and Development of SPH3127, A Novel Highly Potent and Orally Active Renin Inhibitor
Guangxin Xia (Shanghai Pharma)夏广新（上海医药集团）
10:10 - 10:30
(Tea break & Poster) 茶歇与海报交流
10:30 - 11:00
Atomistic Simulation of Sodium-coupled Solute Transport
Jing Huang (Westlake University) 黄晶 （西湖大学）
11:00 - 11:30
Mechanistic insights into the allosteric activation of YopJ family acetyltransferases
Zhiming Zhang (Jinan University) 张志民 （暨南大学）
11:30 - 12:00
Precise Asymmetric Synthesis and Its Application for Highly-efficient Construction of Bioactive Molecules
Shouguo Wang (Shenzhen Institutes of Advance Technology, CAS) 王守国 （中科院深圳先进技术研究院）
12:00 - 13:30
(lunch and break) 午餐与休闲
13:30 - 14:10
Development of Novel Therapeutics in Oncology
Peter Lobie Tsinghua Graduate School Shenzhen (清华大学深圳研究生院)
14:10 - 14:40
Discovering First-in-Class Drugs from Basic Science Breakthrough and with Collaborating Pharma Partners
Yuanxin Fu (West China Hospital，Sichuan University) 傅新元（四川大学华西医院）
14:40 - 15:00
Enabling rational morphology design and crystal engineering with software for mechanistic crystal growth models
Peng Zhu (Zhuhai Institutes of Advanced Technology) 朱鹏 （珠海先进技术研究院）
15:00 - 15:20
(Tea break & Poster) 茶歇与海报交流
15:20 - 15:50
Cocrystallisation as a means to modify drug properties
Stephen Chan (Shenzhen Institutes of Advance Technology, CAS) 陈显翀 （中科院深圳先进技术研究院）
15:50 - 16:20
Structural distinctions between NAD+ riboswitch domains 1 and 2 determine differential folding and ligand binding
Aiming Ren (Zhejiang University)任艾明 （浙江大学）
16:20 - 16:50
Understanding Peptide Self-Assembly with Multiscale Molecular Simulations for Design of Nanomaterials
WeiHan (Peking University Shenzhen Graduate School.) 韩伟 （北京大学深圳研究生院）
16:50 - 17:20
Cryo-EM structures of the AVP-vasopressin receptor 2-Gs signaling complex
Yang Du (Hongkong Chinese University Shenzhen) 杜洋 （香港中文大学深圳）
9:00 - 9:40
“Protein Medical Engineering”: Semisynthetic sensor proteins for clinical metabolic assays and NAD+ drug screenings
Qiuliyang Yu (Shenzhen Institutes of Advance Technology, CAS) 於邱黎阳（中科院深圳先进技术研究院）
9:40 - 10:10
Protein-protein interaction network-based methods for disease genes and drug targets prediction: some cases study
Guang Hu (Suzhou University) 胡广 （苏州大学）
10:10 - 10:40
Introduction to PROTAC Drug DiscoveryTechnology
Huaqing Liu (BeiGene Inc) 刘华庆 （百济神州）
10:40 - 10:50
(Tea break & Poster) 茶歇与海报交流
10:50 - 11:20
Computational pharmaceutics - a new paradigm of drug delivery
Defang Ouyang (Macao University)欧阳德方 （澳门大学）
11:20 - 11:50
Cdc20 PROTACs inhibitors block mitotic progression for cancer therapy
Hongchun Li (Shenzhen Institutes of Advance Technology, CAS) 李红春 （中科院深圳先进技术研究院）
11:50 - 11:55
Summary of the event会议小结
13:30 - 16:30
Tour in Zhuahai游览珠海
